Recent advancments in drug delivery have led to improved precision in delivering medications to specific area. This is archived by using nansensores, which are capable of detecting specific cells and regulating the release of drugs. These curting-edge medications are commonly referred to as smart drugs. Conventional chemorherapy drugs function by targeting rapidly deviding cells, a key characteristic of cancer cells. The majoraty of anticancer drugs have a restricted theraputic range, which frequently leads to toxicity in rapidlly proliferating normal stem cells, including those found in rhe gasterointentestinal tract (GIT), macrophages, bone marrow, and hair follicles. This toxicity resulted in various adverse effects such as alpopecia (hair loss), thrombcytopenia/anemia, organ dysfunction, mucositis (an inflammatory condition of the covering cella of GIT), myelosuppression (reduced proudution of white blood cells, leading to immunosuppression), and other hematological side effects. Doxorubicin is used in the treatment of several types of cancer, such as Hodgkin's disease, in conjuction with other antineoplastic drugs to reduce its toxicity. Paclitaxal is an interavenously administered medication utilized for the treatment of breast cancer. Notable adverse effects encompass progressive neurotoxicity and bone marrow suppression. Cisplatin in an alkylating agent that form covalant bonds within DNA strands. The adverse effects of its use include dizziness and intense emesis, and it possesses nepherotoxic properties. Several endeavors have been initiated with the aim of utilizing nanotechnology to construct drug delivey systems (DDS) that can mitigate the adverse effects of conventional treatments. Dox was deposited onto the outer surface on single-walled carbon nanotubes. The polymer prodrug/collagen hybrid of Dox was employed in metastatic tumor cells. The application of polymer prodrug nanoscales in the treatment of rapodlly proliferating abberrant cells represents a groundbreaking advancement in the area. Nanotechnology is always seeking biocompatible compunds to serve systems. The use of nanoscale hydroxyapatite, a crucial constituent of teeth and bone, was used for the delivery of paclitaxel, an anti-neoplastic drug.The results indicate that tratment should commence with hydrophobic medications. Several projects have been undertaken to utilize nanotechnology in the fabrication of DDSin order to reduce adverse effects of conventional treatment methods. The drawback of cautious chemotherapeutics is their inability to selectively target cancer cells. Nanorobots, which can move through the bloodstream, have the potential to assist in importants medication processes, including early diagnosis and precise drug delivey. A nonorobot can assist in targeted chemotherapy by selectively delivering medicine to neoplastic-specific cells and tissuse while minimizing harm to surrounding healthy cells. Nonorobots serve as drug carriers to provide precise timing of medication delivey, enablingchemical agents to remain in circulation for the necessary duration. This facilitates the desired pharmacokinetic prperties, enabling chemotherapy in anticancer treatments. Nanorobots can be delivered intravenously to facilitate their clinical application in diagnostics, treatment, and surgical procedures. The nanorobots can be given intravenously into the recipients's body. Chemotheraputic drugs include the processes of absorbrion, metabolism, and elimination, along with a time of rest for the body to recover before the next chemotherapy treatment. Nonorobots can serve as an initial time thershold for medical reasons by efficiently evaluating and diagnosin tumors usnig sensores based on proteomics. The kinetics of contrast-agentabsorbtion using magnetic resonance imaging can predict the delivery of protein theraputics to solid tumors, especially when the molecular weigh is relatively small.